Bioidentical progesterone cream side effects and bioidentical estrogen cream side effects may not be severe but you need to be aware of them and know how you can respond to them. There are really three categories of bioidentical progesterone cream side effects and bioidentical estrogen cream side effects:
- Side effects that occur at the site where you put the cream
- Side effects that occur right after the ingredients have been absorbed
- Side effects that happen in the longer term
This post goes over all of the bioidentical progesterone cream side effects and bioidentical estrogen cream side effects that commonly occur with suggestions about what to do. That said, if you experience any side effect of bioidentical progesterone or estrogen creams, you should check in with your doctor.
(This post focuses on specific effects of the cream solution. Of course you may have side effects from the chemistry, similar to what you would have had had you used BHRT pills and supplements. Make sure to read our more general bioidentical hormone replacement side effects page as well as our page answering “Are bioidentical hormones safe?”.)
Bioidentical Estrogen Cream Side Effects
Bioidentical estrogen cream side effects are not common, at least those that are moderate to severe. That said, you may experience some of the more mild effects especially when you first use a cream or when you use a product containing a new ingredient. The bioidentical estrogen cream side effects you might experience include:
Application site bioidentical estrogen cream side effects
You might experience redness or itching where you put the cream on. Some people also develop a mild rash. If you have sensitive skin you may want to talk to your BHRT doctor ahead of time to ask where you should apply the cream to minimize these effects. If the redness, itching, or rash in more than mild or persists, you should consult your doctor. Starting with a lower dose to check for these types of potential reactions can be a good idea. If they are mild you may be able to merely rotate where you apply the product to minimize the reactions. The main initial bioidentical estrogen cream side effects are these, and you should be prepared for at least a mild skin reaction.
Initial Side Effects of Bioidentical Estrogen Cream
Once the cream is absorbed you might experience internal effects such as headache and nausea. You should refer to general information about the side effects of bioidentical estrogen and realize that just because you used the cream transdermally this does not mean you will definitely be free of the same issues. If you experience breast tenderness, cramping, or spotting let your doctor know. If you have headaches, nausea, or insomnia you might also want to let her or him know. These issues may resolve and may be mild to begin with, but it is still worth getting them checked out.
Longer term side effects of bioidentical estrogen cream
While there is a lot of worry about longer term side effects of bioidentical estrogen cream and BHRT in general, you should be aware that these ingredients have been used for some time. If you are in the U.S. you should know that bioidenticals have been popular in Europe for much longer than they’ve been used here, so there is evidence that they do not cause long-term problems that would not be seen with synthetics. That said, you should ask your doctor for information about the long-term effects of the ingredients that are in your formula, and research them yourself.
What to do if you experience bioidentical estrogen cream side effects
If you do start to experience any new issues after having taken bioidentical estrogen cream for a while make sure to see your doctor right away. Again, while the long-term side effect profile of these creams do not seem more severe than their synthetic counterparts, that does not mean that there are no possible long-term effects.
Bioidentical Progesterone Cream Side Effects
Bioidentical progesterone cream side effects are also not common, and generally no more severe or common than those you might have with synthetics. That said, as above we wanted to go over some of the possible unwanted effects you might experience.
Application site bioidentical progesterone cream side effects
Similar to the above you should look for redness, rashes or itching where you use the cream. Those with sensitive skin should talk to your BHRT doctor, and you may want to carefully choose where you apply it so that these effects are not noticeable and may be less severe. If your reaction is mild that may be okay, but if it is more severe or persists you should talk to your BHRT doctor. We suggest that it is worthwhile to use only a minimal amount of bioidentical progesterone cream at first to test for potential skin reactions especially if you have sensitive skin. Then rotating where you put the cream on can minimize a worsening of any mild bioidentical progesterone side effects you experience.
Initial Side Effects of Bioidentical Progesterone Cream
As with estrogen you may experience a mild headache or nausea after the skin cream is absorbed when you first start using this cream. While you should still report these issues to your BHRT doctor, you may find that the symptoms disappear after your body gets used to these ingredients. Whether you continue may be determined by how severe the reactions are and how long they last. If you experience more serious initial side effects of bioidentical progesterone cream including cramping, spotting, insomnia, or vomiting let your doctor know right away. She or he may not need to stop using bioidenticals but you may need to try a different formula, means of taking them, or dose.
Longer term side effects of bioidentical Progesterone cream
You should ask your BHRT doctor for guidance about the potential longer-term side effects of the ingredients in your unique formula, and also look into them for yourself. While these formulas may prove safer than synthetic choices, that does not mean that you will certainly be free of longer term effects altogether. If you experience any changes such as increased anxiety, mood swings, and depression you should at least check in with your doctor. If you experience other physical symptoms you should check in with your doctor and make sure you are fully aware of the ingredients in your bioidentical progesterone cream when you do.
Bioidentical estrogen cream side effects and bioidentical progesterone cream side effects are not common, at least those that would be severe enough that you’d want to stop taking the hormones. For many people the benefits of using one of these approaches are worth putting up with some mild side effects. That said, you need to watch for side effects of bioidentical estrogen cream or side effects of bioidentical progesterone cream that worsen over time, persist, or are moderate to severe in the first place. Stay in touch with your practitioner about all of this. She or he may be able to make a change in formula, application site, or dose that can address any untoward effects.
Bioidentical estrogen cream side effects conclusions
Bioidentical estrogen cream side effects are unlikely to be severe enough for you to stop the treatment altogether. They may warrant either backing off on the dose or changing the application type of site. For some the side effects of bioidentical estrogen cream go away after a short while, so you should inform your doctor about everything from headaches to breast tenderness to rash.
Bioidentical progesterone cream side effects conclusions
As above, the side effects of bioidentical progesterone cream may not be severe enough or last long enough to warrant coming off of the treatment. Changing the method, dose, or site of administration may be enough. That said, the bioidentical progesterone side effects may be more severe than those you experience with estrogen, so make sure to tell your doctor about any persistent cramping, insomnia, or moodiness.
This website has a nice and comprehensive overview of the possible side effects of bioidentical cream as well as what to do about them. You should also have a talk with your doctor about any cautions that may be unique to you given your medical history and other aspects or your exam. She or he will want to watch for any problems, and keep in mind that just because you experience an unwanted reaction that does not mean you will be pulled off of BHRT.
We would like to hear from you about any experiences you had with these creams:
- What side effects from bioidentical cream did you experience?
- What did your practitioner suggest you do to reduce their effects or intensity, and did these solutions work?
- Were the benefits enough to outweigh the side effects from bioidentical cream?
Best of luck with your course of treatment, and we hope that you do not experience prohibitive side effects of bioidentical estrogen cream or side effects of bioidentical progesterone cream!